Bird flu continues to pose a growing global threat. In large parts of the world, millions of animals are being culled, with soaring economic costs. Moreover, there are continuous concerns regarding the threat bird flu poses to human health. How do we get a better grip on this situation and what does the future of avian influenza look like? What can we do in terms of diagnostics and management and how can we manage the potential threat of zoonosis?

We have joined forces with Alveo Technologies, Inc. (Alveo) to deliver a transformative point-of-care testing solution for farm animal health and welfare. By combining Alveo’s molecular testing platform with GD’s veterinary expertise, we make a powerful step forward in enabling fast, accurate, and accessible diagnostics at the point of need.

Cutting-Edge Technology for Immediate Results

This partnership development leverages Next-Generation Nucleic Acid Amplification Testing with loop-mediated isothermal amplification. Unlike conventional optical detection methods, Alveo Sense employs direct electrical sensing, making it faster, more reliable, and easier to use in the field.

The single-use microfluidic cartridges used in the test can simultaneously detect Avian Influenza virus (AIV) M-gene and critical subtypes H5, H7, and H9 without the need for RNA extraction or specialized laboratory equipment. Delivering results within 45 minutes, this point-of-care approach ensures rapid decision-making, essential for preventing disease spread and mitigating economic losses.

 

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Key Advantages Over Traditional RT-PCR

Unlike RT-PCR, which requires specialized lab infrastructure and trained personnel, Alveo Sense offers a point-of-need solution that is portable, easy to use, and requires minimal training. With USB-C charging, minimal consumables, and cloud-based data collection, the device provides real-time insights accessible from anywhere.

Why Alveo Sense?

  • Plug & Play Simplicity – Minimal training required, easy-to-use technology
  • Lightning-Fast Results – Get answers in just 45 minutes
  • Portability & Convenience – USB-C charging, minimal consumables, and a robust design for field use
  • Real-Time Decision-Making – Cloud-based data sharing and geolocation tracking
  • Cost-Effective – No costly lab infrastructure or specialized technicians needed

Validation and Performance

Field validation studies demonstrate >99% specificity for AIV subtypes without cross-reactivity. Sensitivity tests show detection at RT-PCR Ct values of 29-33 for H5, H7, and H9 in cloacal and oropharyngeal samples. The test maintains stability across different conditions and users, ensuring high reproducibility.

Impact on the Poultry Industry

Alveo Sense offers a game-changing approach to avian influenza surveillance, enabling veterinarians and poultry producers to act swiftly. With traceability, geolocation tracking, and cloud-based data management, it enhances disease monitoring and facilitates regulatory compliance. Alveo Sense facilitates a differentiating infected from vaccinated animals (DIVA) vaccination strategy when used in conjunction with the administration of inactivated avian flu vaccines. Successful application of inactivated avian flu vaccines in the absence of field virus infection will yield a negative result. In this way, the avian flu status of a flock can be clearly identified. As avian influenza continues to pose a global challenge, Alveo Sense provides the poultry industry with a fast, accurate, and accessible diagnostic tool, setting a new standard for biosecurity and disease control.

Sample collection to results in less than one hour

PCR-like results without the complexity or expensive equipment

A molecular testing laboratory in the palm of your hand. This streamlined workflow delivers actionable results in less than an hour. Experience fast, reliable, Bluetooth-connected molecular testing designed for on-the-spot decision making. The Alveo Sense has multiplexed panels for all relevant strains of AI type A viruses, with differentiation of H5 and H7 or H9 subtypes. The device offers 100% sensitivity and specificity for all targets.

More information about Alveo Sense
Find out more about Alveo and Alveo Sense and request a quote directly. 
Alveo Sense | Avian Influenza Test Request a quote Alveo Technologies

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